Supportive Oligonucleotide Therapy (SOT) in Fairfield, CT
Advanced SOT Treatment for Chronic Lyme Disease
If you’re living with Lyme disease, you know how disruptive and uncomfortable it can be, especially when standard treatment hasn’t resolved it. We offer Supportive Oligonucleotide Therapy (SOT), a targeted treatment that works at the source of the infection, not just the symptoms.
What Is Supportive Oligonucleotide Therapy (SOT)?
SOT, also called antisense therapy, uses your own blood to create a customized treatment that targets the specific pathogens driving your Lyme disease. It works by creating synthetic RNA strands that disrupt the messenger RNA responsible for producing proteins the bacteria need to survive, cutting off their ability to replicate.
SOT is also used in cancer and muscular dystrophy treatment, and research has shown it to be a promising option for Lyme disease specifically.
Early symptoms (within a month of a tick bite)
- Flu-like illness with fever, chills, and muscle aches
- Swollen, tender lymph nodes near the bite
- Erythema migrans (bullseye rash), when present
As the infection spreads
- Joint pain and swelling
- Fatigue
- Headaches and dizziness
- Brain fog and memory issues
- Photosensitivity
- Tingling and numbness
Left untreated, long-term effects can include
- Arthritis, especially in the knees
- Irregular heart rhythm
- Neurological problems
- Impaired muscle movement
Lyme disease can also trigger neurological symptoms that persist even after treatment. If brain fog, memory issues, or nerve-related symptoms are a major part of your case, our Neurology care works alongside Lyme treatment to address these specifically.
How Does SOT Treat Lyme Disease?
Each SOT treatment is built around a “key and lock” mechanism: the synthetic RNA strand is designed to fit a specific part of the pathogen’s genetic material. When enough of these “keys” reach their targets, the bacteria can no longer survive, and your overall disease load decreases.
What to Expect During SOT Treatment
Treatment starts with blood testing to understand how Lyme disease is affecting your system. A blood draw then provides the material used to create your customized SOT solution. Once it’s ready, the solution is administered intravenously so the treatment enters your bloodstream directly.
SOT then seeks out the bacteria causing your Lyme disease and embeds itself within those molecules, stopping them from replicating. It’s often used alongside antibiotic therapy for a more complete approach. Before your infusion, your provider administers antihistamines and steroids to support your vein walls and reduce the risk of an allergic reaction.
In-office infusions take about an hour, require no anesthesia, and you can return to your day immediately afterward.
How Long Do SOT Results Last?
For most patients, results last 3-6 months. Additional blood testing helps determine how well the treatment is working and whether you need another round, up to three times per year, to keep Lyme disease under control.
Serving Fairfield and Surrounding Connecticut Communities
Our SOT program is based in Fairfield, CT, and we treat patients from throughout the surrounding area, including Westport, Norwalk, Bridgeport, Trumbull, Stratford, Easton, Weston, and greater Fairfield County. If you’ve been searching for Lyme disease treatment near you and haven’t found a provider offering SOT, our team is here to help.
Why Patients Choose Fairfield Family Health for SOT
Specialized Lyme Disease Focus
SOT is offered alongside our broader Lyme disease treatment protocols, not as a standalone, disconnected therapy.
Personalized, Blood-Based Treatment
Your SOT solution is built specifically from your own blood work, not a generic formulation.
Coordinated with Antibiotic Therapy
When appropriate, SOT is combined with antibiotics for a more complete treatment approach.
Comfortable, In-Office Infusions
Sessions take about an hour, require no anesthesia, and fit into your day with no downtime.
Frequently Asked Questions
What is Supportive Oligonucleotide Therapy (SOT)?
SOT is a treatment that uses synthetic RNA strands, built from your own blood, to target and disrupt the bacteria responsible for Lyme disease.
How long does SOT treatment take?
In-office infusions take about an hour. Results typically last 3-6 months, with additional rounds available up to three times per year.
Is SOT used with antibiotics?
Yes. SOT is often used alongside antibiotic therapy for a more complete treatment approach to Lyme disease.
Is SOT safe?
Before your infusion, your provider administers antihistamines and steroids to support your vein walls and reduce the risk of an allergic reaction. No anesthesia is needed.
Do I need a referral for SOT treatment?
No referral is required. You can call our office or book an appointment online.
Get Advanced Lyme Disease Treatment in Fairfield, CT
If standard treatment hasn’t resolved your Lyme disease, our team can help you find out if SOT is the right next step.